Excellent presentation. I happened to see another discussion just today about the same topic The two presentation styles of the same issue really helps provide clarity. Probably have too review both a few times to get "complete" clarity
The idea of the permanence of the glycated protein till cell death/autophagy is quite sobering. As sobering as aging. Nothing is perfectly reversible. And glycation seems particularly irreversible. Intuitively (perhaps incorrectly) it helps explain to me why kidney damage (often related to excess sugar) is virtually irreversible. If you got the damage from glycation it would appear that those glycated cells are not going to magically cleanse themselves of the nasty sugar because there is no enzyme to do it. It would suggest (to me) that the only thing that may help (just speculating) is fasting and autophagy. And of course as the video said, never a bad time to get off your but and exercise. Basically you have too regenerate because you can't fix it.
In theory (if the fasting theory has any merit at all) it would make sense but you can only do so much fasting and so much autophagy so your best bet is be studious about taking care of your metabolic health and not get in trouble to start. Or at least slow it down till you're 150 or whatever. By that time you've earned the right to a donut:). Sugar damage may (or may not) be slow but reversing the damage is either impossible or so slow it hardly can exceed the rate you are aging.
Next time I go for a donut I'll use the imagery of permanently glycated (damaged) cells to help me resist. You'd think losing toes or kidney function would be enough to motive anyone but when it comes to resisting donuts and ice cream we need all the imagery we can muster
Excellent presentation. I happened to see another discussion just today about the same topic The two presentation styles of the same issue really helps provide clarity. Probably have too review both a few times to get "complete" clarity
The idea of the permanence of the glycated protein till cell death/autophagy is quite sobering. As sobering as aging. Nothing is perfectly reversible. And glycation seems particularly irreversible. Intuitively (perhaps incorrectly) it helps explain to me why kidney damage (often related to excess sugar) is virtually irreversible. If you got the damage from glycation it would appear that those glycated cells are not going to magically cleanse themselves of the nasty sugar because there is no enzyme to do it. It would suggest (to me) that the only thing that may help (just speculating) is fasting and autophagy. And of course as the video said, never a bad time to get off your but and exercise. Basically you have too regenerate because you can't fix it.
In theory (if the fasting theory has any merit at all) it would make sense but you can only do so much fasting and so much autophagy so your best bet is be studious about taking care of your metabolic health and not get in trouble to start. Or at least slow it down till you're 150 or whatever. By that time you've earned the right to a donut:). Sugar damage may (or may not) be slow but reversing the damage is either impossible or so slow it hardly can exceed the rate you are aging.
Next time I go for a donut I'll use the imagery of permanently glycated (damaged) cells to help me resist. You'd think losing toes or kidney function would be enough to motive anyone but when it comes to resisting donuts and ice cream we need all the imagery we can muster