Video notes: BA.4 and BA.5 Have Significantly Escaped Protection From Vaccines and Infections

A summary of the impact of the immune escape

BA.4 and BA.5 Have Significantly Escaped Protection From Vaccines and Infections

Researchers own summary first then my comments and references after:

These data show that the BA.2.12.1, BA.4, and BA.5 subvariants substantially escape neutralizing antibodies induced by both vaccination and infection. Moreover, neutralizing antibody titers against the BA.4 or BA.5 subvariant and (to a lesser extent) against the BA.2.12.1 subvariant were lower than titers against the BA.1 and BA.2 subvariants,